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If any participants or their legal guardians ask to cease interventions, we will finish those

Supplementation restores what time depletes while supporting skin integrity during body composition changes

The four-pathway model therefore targets appetite (GLP-1 and amylin through separate neuronal circuits), fat metabolism (GIP and glucagon), energy expenditure (glucagon primarily), and glucose homeostasis (GLP-1, GIP, and amylin all contribute through different mechanisms)