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First week: Mild nausea, fatigue, or headaches are most common Weeks 24: Symptoms often lessen as the body adapts After one month: Many people report minimal or no ongoing side effects Side effects may briefly return after dose increases, then improve again

To support this perspective, Nardone and colleagues found a combination of clinical/dermatoscopic findings and FISH enhanced detection in a subset of patients with early melanoma, including cases where Spitz nevus was on the differential [54]

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