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The data were, however, not compatible with a protective intention-to-treat effect. They concluded: Randomized trials using MALO as an outcome might be unfeasible, motivating further large observational studies using appropriate methodology to further delineate the effect of GLP1 agonists on the risk of MALO, complementing future phase 3 trials of GLP1 agonists.

In May, Australia banned compounded GLP-1s citing safety concerns

This feature of DFO makes it a selective chelating agent for iron and aluminium, and following chelation, it results in molecules of ferrioxamine and aluminoxamine, respectively being formed

However, MT-2 is not FDA approved, and long-term safety data is limited