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A stratified Cox proportional hazards model was used, with treatment as a fixed effect and trial-level cardiovascular risk as the stratification factor, to estimate hazard ratios (HRs) and confidence intervals (CIs) when comparing tirzepatide to the control

Glycine concentrations in compounded tirzepatide formulations vary by pharmacy, typically ranging from 10 mg to 30 mg per injection dose

Fatigue and weakness may occur, particularly during the initial treatment period as the body adjusts to the metabolic effects of the medication

The addition of glycine and vitamin B12 is intended to support patients experiencing issues such as fatigue, muscle loss, or neuropathycommon concerns during weight loss or diabetes treatmentand may offer metabolic, neurological, and musculoskeletal benefits