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137 As a sulfur-containing amino acid, it possesses two potential binding sites for metals and is capable of binding and sequestering divalent copper (II), trivalent iron (III), lead, mercury, and cadmium ions

In patients with diabetes, there is the development of a phenomenon called oxidative stress where bad compounds in the body, such as free radicals become present

Whereas autophagy can degrade large macromolecular complexes and even entire organelles, the UPS is characterized by exquisite substrate specificity, targeting only ubiquitinated proteins while preserving intact cellular structures

Geneva: WHO (2018)