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3.2 ACE2/Ang-(17)/MasR and antidepressant/anxiolytic effect Walther was the first to discover that the ACE2/Ang-(17)/MasR pathway is associated with the development of anxiety, demonstrating that upregulating ACE2 significantly improved anxiety-like behaviors ( 1 R pathway

NAC is able to partially protect from oxidative stress and GSH decrease, while enhancing GSH synthesis and restricting GSH loss [39]

Rodrguez-Gmez FD, Monferrer D, Penon O, Rivera-Gil P (2025) Regulatory pathways and guidelines for nanotechnology-enabled health products: a comparative review of EU and US frameworks

4 , 5 The rarity of diphtheria in high-income settings may delay the diagnosis until an advanced stage, 3 , 6 increasing the risk of potentially fatal outcomes