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Sources: Research on berberine indicates several notable benefits and effects: Blood Sugar Regulation : Berberine significantly lowers blood glucose levels, akin to the effects of prescription medications like Metformin

& Ingelsson, E

But individuals starting semaglutide who are also dealing with GI side effects, reduced food and fluid intake, and the physiological stress of early dose escalation may notice this elevated baseline more acutely than someone in a controlled trial environment