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doi: 10.3389/fphar.2024.1471615 Received 28 July 2024 Accepted 10 October 2024 Published 22 October 2024 Volume 15 - 2024 Edited by Felice Strollo, Endocrinology and Metabolism Unit, IRCCS San Raffaele Pisana, Rome, Italy, Italy Reviewed by Sandro Gentile, University of Campania Luigi Vanvitelli, Italy Maja Cigrovski Berkovic, Clinical Hospital Dubrava, Croatia Updates Copyright 2024 Zhang, Wang and Zhou

Rising value of non-natural amino acids and special building blocks Next-generation peptide drugs rely increasingly on: Non-natural amino acids Structural stabilization modifications Half-life extension strategies Aib (-aminoisobutyric acid) is one of the most important examples