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Dihexa offers a potentially more targeted synaptogenic effect based on its unique HGF/c-Met mechanism, and its oral availability makes it more accessible than injectable peptides

However, although the macrocycles immobilized on the SPR sensor chip showed strong binding profiles to the human ectodomain, binding was detected to neither the murine nor the canine ectodomains (Supplementary Table 3 and Supplementary Fig

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