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This sensation can be intense, making you feel overheated and uncomfortable

Wait until nausea has a natural lull for most people, mid-morning (after the immediate post-injection window) tends to be the most tolerable time

For example, exendin and exenatide, two GLP-1 RAs, have been shown to suppress macrophage secretion of multiple pro-inflammatory cytokines, including IFN-, IL-17, IL-2, TNF-, IL-6, and IL-1 (103, 105)