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These include: Nausea and vomiting Diarrhoea Abdominal discomfort Constipation When patients experience significant nausea or gastrointestinal distress, the body's autonomic nervous system may respond with sweating, particularly cold sweats or diaphoresis

Nonetheless, the widespread distribution of these receptors raises concerns about potential unintended physiological effects associated with GLP-1RAs

Researchers also noted the potential for gallbladder-related events, consistent with rapid weight loss from any cause