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Phase 2 trial (NEJM 2023) used a structured ramp to 12 mg/week but at trial doses of 8 mg and 12 mg, dropout from gastrointestinal events was substantial
[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Ansari M.A., Chauhan W., Shoaib S., Alyahya S.A., Ali M., Ashraf H., Alomary M.N., Al-Suhaimi E.A
TRG sensitized chemo-resistant head and neck cancer (HNC) cells to in vitro and in vivo RSL3 treatment by decreasing the activity of the Nrf2-ARE pathway (Shin et al., 2018)
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