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however, alternatives have been developed given the concern for side effects of hydroquinone

A few mention gastrointestinal upset with certain fillers or coatings

Since mature erythrocytes are not capable of expressing proteins, their antioxidant defense system has a limit of the concentration of the stress inducer or its intake rate, after which it cannot cope with the stress 16,19,45,64

Ecology 90(4):912920 Hawkins TD, Krueger T, Becker S, Fisher PL, Davy SK (2014) Differential nitric oxide synthesis and host apoptotic events correlate with bleaching susceptibility in reef corals