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J Endocrinol Metab

PF4 is a 70aa protein that is member of the CXC ELR- family of chemokines that is able to potently inhibit endothelial cell proliferation in vitro and angiogenesis in vivo

(2016) Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity Ryan, Donna H., Ryan Yockey, Sarah (2018) Weight Loss and Improvement in Comorbidity: Differences at 5%, 10%, 15%, and Over Brown, Joshua D., et al (2015) Effects on cardiovascular risk factors of weight losses limited to 510% Georgoulis, Michael, et al

It may also be suitable for individuals with conditions such as type 2 diabetes or cardiovascular disease