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The hypothalamus as the central regulator of energy balance and its impact on current and future obesity treatments

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10.1016/S2468-1253(21)00065-0

As most of these studies only followed patients for a few weeks after stopping the drugs, the team selected the six RCTs (comprising more than 3,200 individuals in total) that followed patients for up to 52 weeks after discontinuation of the weight loss drugs