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There was no significant increase in atrial fibrillation (in line with a previous meta-analysis 59 ), atrial flutter, ventricular arrhythmia, or sudden cardiac death, although it was noted that higher doses of GLP-1 RAs may increase the risk of ventricular arrhythmia

The present study demonstrated that semaglutide treatment further enhanced the H/R-induced changes in autophagy activity, autophagosome levels and LC3-II/LC3-I ratio, suggesting a regulatory role of semaglutide in autophagy

KOCMP-14652-Glp1r) were purchased from Cyagen Biosciences (Suzhou, China)

Notably, cerebral dysfunction has been identified as a potential extrahepatic symptom of NAFLD (284)