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doi:10.1046/j.1523-1747.1998.00381.x CrossRef Berlanga-Acosta J, et al
Because patients with DS have extra chromosome material, they experience genetic overexpression of specific amino acids and polypeptides
This is clearly demonstrated in people living with DS, where the overexpression of CBS is a genetic consequence that causes a significant reduction of serum homocysteine concentration leading to less available methionine within the methionine cycle
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