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This rising prevalence - influenced by aging populations, sedentary lifestyles, and increasing obesity rates - ensures sustained demand for improved therapies and intervention strategies

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Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive inflammatory form, metabolic dysfunction-associated steatohepatitis (MASH), constitute an escalating worldwide health challenge, with prevalence estimates reaching one-quarter of adults globally

Briefly, the GLP-1R reporter cells were seeded into white-bottom 96-well assay plates in cell recovery medium (200 L/well) and incubated at 37 C in a humidified atmosphere of 5% CO 2 for 5 h