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Kanai R, Kinoshita S, Kanbe I, et al

Your body is adjusting to a new medication that fundamentally changes how your digestive system operates

It has Anti-inflammatory action because it reduces proconvulsant cytokines such as IL-1 and TNF-, which are linked to increased seizure susceptibility

In published Phase 2 clinical studies, retatrutide was evaluated using once-weekly dosing schedules , with doses escalating up to 12 mg over a 48-week treatment period