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7 For now, more than 100 T2D-susceptibility genes have been mapped in human including TCF7L2, GCK, KCNJ11, PPARG

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Moreover, one recent study (119) showed that lixisenatide exerted neuroprotection potentially by downregulating levels of NF-B, TLR2/4, MPO, and pP38 as well as upregulating expression of pERK1/2

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