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Interestingly, despite the presence of superoxide dismutase (SOD) ( k = 2.4 10 9 M 1 s 1 ) 36 , the resulting concentration of H 2 O 2 is significantly smaller than the concentration of superoxide, indicating that the model is able to respond well to a transient increase in ROS, maintaining low H 2 O 2 concentrations
While glutathione is generally safe for healthy individuals, extra caution is needed if: You have chronic kidney disease You have impaired kidney filtration You are on multiple medications You have liver or metabolic disorders In these cases, always consult a healthcare professional first