A subset of genes was differentially expressed in all treatments/timepoints when UQCR-C1 was silenced, and multiple genes were differentially regulated only at specific timepoints or upon infection (all significantly differentially expressed genes are listed in Additional File 6)
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Subsequent increases in the permeability of the intestinal barrier in CKD patients promote the translocation of bacterial products of intestinal origin, such as LPS, uremic toxins, and cytokines, into the systemic circulation, resulting in local and systemic inflammation, as well as oxidative stress associated with CKD (Krukowski et al., 2023
Surface activity in vitro: role of surfactant proteins