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Numerous studies centred on GST gene polymorphisms as factors modulating the risk of developing cancer 32

i 2+ K : Beta-2 receptor stimulation has been shown to stimulate calcium-activated potassium (KCa) channels in airway smooth muscle by both PKA-induced phosphorylation, and membrane-delimited Gs pathways (Kume et al, 1994)

353 (8), e2000081

Genetic testing was also performed for CYP2C9 (*2, *3), CYP2C19 (*2,*3,*17) and CYP3A5*3, known to be involved in tamoxifen metabolism using TaqMan or Sequenom mass array genotyping