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Gel formulations of vitamin B12 are somewhat new and applied into the nostrils (intranasally)

Once the quantity of vitamin B12 that is absorbed in the body is sufficient, patients should notice a significant increase in their energy levels, an improvement in their overall cognitive functioning that may improve their memory and ability to think, as well as a considerable boost to their general mood

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1864 (11), 2015-2025

Andersson, Emmanuel Shapira, Biochemical and clinical response to hydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonic acidemia and homocystinuria (cblC), The Journal of Pediatrics, Volume 132, Issue 1, January 1998, Pages 121-124, ISSN 0022-3476, Okuda K, Yashima K, Kitazaki T, Takara I