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Description

In a first exploratory clinical trial in patients with refractory chronic cough, daily nasal treatment with an alkaline hypertonic divalent salt pH 9 aerosol (SC001) reduced daily cough rate by up to 35% relative to a nasal saline control 247

The cells were transfected with empty plasmid vectors or plasmids using Lipofectamine 2000 (Invitrogen, Waltham, MA, USA) according to the manufacturers instructions