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People taking diabetes medications should be cautious, as the combined effects of both MOTS-c supplementation and diabetes medications on blood sugar have not been studied extensively in humans

Oral Treatment Without GI Issues (Future) Bioglutide Phase 2 reported lower GI adverse events compared to existing GLP-1 therapies, though this requires confirmation in larger trials

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Ultimately, choosing between the two medications should involve a discussion with a licensed healthcare provider, considering individual weight loss goals, health history, and treatment preferences