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Major trends: Shift from general 'detox' claims to specific liver function support, Increased use of glutathione in combination with milk thistle and N-acetylcysteine, Growth of liver health awareness campaigns by healthcare professionals, and Rise of at-home liver function testing kits

Each group received subcutaneous injections of semaglutide (30 nmol/kg), tirzepatide (10 nmol/kg), or an equivalent volume of saline once every 3 days over a 7-week period, with the timeline illustrated in Figure 1

GLP-1Rs are densely expressed in the area postrema in rats (182)

Others alternate between abdomen, right thigh, left thigh, and upper arm on a four-week cycle