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This failure is largely due to testing exclusively on cancer cell lines grown in liquid medium, a condition that predicts in vivo efficacy to anticancer drugs worse than cell culture in 3D gels [4, 5] and is far from adequately reflecting the therapeutic responsiveness of cancers within their native microenvironment [2, 3]

Marijuana specifically refers to cannabis products that are made from the dried flowers, leaves, stems and seeds of the cannabis plant.

Dual action of the active oxygen species during plant stress responses