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This is another area of active debate

Some theorize that this is part of the reason why young people experience few ill effects of smoking, but the habit wreaks havoc on their bodies as they age

In addition, these studies confirm that that the endogenous level of brain HGF is sufficient to support Dihexa's neuroprotective/neurorestorative activity and are in concert with the high levels of c-Met in the brain

While no formal clinical trials of this specific combination have been publicly reported as of early 2026, the theoretical basis for synergy is compelling based on the distinct yet complementary mechanisms of each compound [5]