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FIGURE 1 Initially, the degradation of extracellular GSH by membrane-bound -glutamyltransferases (GTs) was considered the major pathway for GSH breakdown ( ChaC-like family proteins are remarkably conserved, being found across all phyla from bacteria to humans, where they catalyze intracellular GSH degradation and yield 5-oxoproline and cysteinylglycine (Figure 2)

Mais on peut sattendre ce que le remboursement soit rserv aux patients fortement obses ou aux patients obses avec des comorbidits et des facteurs de risques cardiovasculaires, ce qui limiterait laccs au mdicament aux personnes qui en ont le plus besoin

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