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However, GLP-1RAs also have separate effects on appetite regulation mediated by actions on central nervous system centers that result in weight loss 15,16

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Thus, the amount of LC3-II is correlated with the autophagy level and is a reliable marker for monitoring autophagy-related processes 21

Seminal work in the late 1960s led to the identification of peptide hormones with glucagonlike immunoreactivity following gastrointestinal tract stimulation by glucose (Samols & Marks, 1967)