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Early-onset type 2 diabetes is not only more aggressive, it usually responds less well to drugs, which means our findings are really encouraging, said Melanie Davies, investigator and Professor of Diabetes Medicine at the University of Leicester, Leicester UK

Moreover, the temporal resolution of fMRI is limited by the haemodynamic response and is substantially poorer than the millisecond-scale neural resolution achievable in animal electrophysiological, optogenetic, or chemogenetic studies

Evidence layer: GLP-1 food-record studies, glucagon/carb mechanism, micronutrient gaps, and sample-day targets sit under the operational how-to