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Ann Surg Oncol 25(7):2012-2017, 2018

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GLP-1Rs are widely expressed in areas of the mesolimbic reward pathway that receive direct projections from the nucleus tractus solitarius (NTS) (Alhadeff et al., 2012)

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Therefore, it is worth evaluating the direct effects of metabolic pathways on KOA, especially in circumstances of obesity and energy deficiency

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