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Assessing the respiratory toxicity of dihydroxyacetone using an in vitro human airway epithelial tissue model

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Case Rep Hematol 2015:180526 Azarkeivan A, Ansari S, Ahmadi MH, Hajibeigy B, Maghsudlu M, Nasizadeh S, Shaigan M, Toolabi A, Salahmand M (2011) Blood transfusion and alloimmunization in patients with thalassemia: multicenter study

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This PEN2-v-ATPase-Ragulator pathway (Figure 1) links metformin to lysosomal nutrient sensing rather than mitochondrial stress, offering a potentially safer mode of AMPK activation

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