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Exploiting this unique property of contractile nanotubes, we can engineer nanotubes with different specificities to target microbes, by substituting the ligand-recognition domains of receptor-binding proteins from phages or from contractile bacteriocins

Western blots Adult retinal tissue pooled from 1-3 fish (tissue from 2-6 eyes) were homogenized in Pierce RIPA Buffer (ThermoFisher) lysis reagent (1 L/mg tissue) supplemented with 1X Halt Protease Inhibitor Cocktail (ThermoFisher) using a sterile microcentrifuge pestle and cordless pestle motor (VWR)

Kurata M, Suzuki M, Takeda K

This widespread receptor distribution means CGRP can influence immune cells, bone-forming cells, and blood vessels simultaneously