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With a growing percentage of the population using these drugs, there is a pressing need for more phase 4 clinical trials to understand their full impact on health and behavior

Coverage that did exist was commonly restricted by prior authorisation requirements, step therapy mandates (requiring failure on cheaper drugs first), and BMI thresholds stricter than the approved labelling

Methods Medline, Cochrane Library, and Scopus were queried through December 2024 for primary and secondary analyses of randomized controlled trials comparing GLP-1RA with placebo in HF patients

Vitamins & Minerals e ating less food often means fewer micronutrients