It functions as a cofactor for lysyl oxidase (the enzyme responsible for collagen cross-linking and stabilization), ceruloplasmin (a copper transport protein with antioxidant activity), and superoxide dismutase (SOD, a primary antioxidant defense enzyme)
Results ACE inhibits proliferation and promotes cell death in colorectal cancer cells Inspired by the problems of drug resistance, metastasis, and side effects of paclitaxel, oxaliplatin, and 5-FU and the advantages of the specificity and broad spectrum of natural drugs used in cancer treatment, we selected RKO cells, a poorly differentiated human colon cancer cell line sensitive to cell death, to screen for antitumor activity in a natural compound library
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