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This increase in intestinal permeability was also observed in rats and Guinea pigs exposed to 5% -PGN in drinking water for 5 months and 6 weeks, respectively (Delahunty, Recher, and Hollander 1987 Delahunty, T., L

The former is a process characterized by mitochondrial swelling, IMM permeabilization and OMM rupture as a secondary event

Keywords Major depressive disorder Carnitine Sertraline Randomized controlled trial INTRODUCTION Major depressive disorder (MDD) is one of the most common psychiatric disorders that affect a large proportion of people, worldwide