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Only two drugs are approved by the FDA for the treatment of EDs: LDX for moderate and severe binge eating in adults aged 18 to 55 and fluoxetine for BN [43]

The approval was based on results from the SURPASS clinical trial program, which demonstrated significant HbA1c reductions and weight reduction benefits, strengthening the adoption of long-acting incretin-based therapies and expanding competition within the GLP-1 analogue market In June 2021, the U.S

This variability may reflect differences in local microenvironmental conditions and responsiveness to treatment 46

In India and most markets outside the US and Canada, the same drug is sold as Forxiga by AstraZeneca Farxiga and Forxiga are identical medications, same active ingredient (dapagliflozin), same dosing, same clinical data