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Emerging evidence also highlights the importance of nutritional interventions to reduce DKD-related complications due to nutrients

The GSK-Harmony data were not included in the meta-analysis due to substantial methodological differences (the option to intensify GLP-1RA therapy in non-responders, measurement of effect over 8 months rather than 6 months and the relatively small glycemic effect seen with albiglutide)

SURMOUNT-1, the pivotal trial in adults without diabetes, demonstrated that participants receiving the highest dose (15 mg) achieved an average weight loss of approximately 20.9% of body weight over 72 weeks, compared to 3.1% with placebo

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