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They activate GLP-1 receptors in your body, leading to an increase in the production of insulin, which helps move glucose into your cells, where its used for energy, Dr

GLP-1 Medications Effective while taking them Can require lifelong use Weight regain common after stopping Real-world adherence varies Cost can be substantial over time Bariatric Surgery Proven long-term weight loss and remission of conditions like diabetes and sleep apnea More durable than GLP-1s alone Supported by decades of data and clinical outcomes Often covered by insurance Includes lifetime follow-up care at Grand Health Partners Studies show bariatric surgery delivers significantly greater long-term results compared to GLP-1 medications

Age also plays a role in adherence, with lower rates observed in younger populations (Chart 6)

In diabetic patients, semaglutide significantly reduced the incidence of cardiovascular events by 26%