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In addition to respiratory and metabolic dysfunction, patients with COVID-19 can experience inflammatory cytokine storms leading to organ failure (12, 13)

Patients should seek immediate medical attention for signs of possible complications such as cellulitis (redness, warmth, fever), deep vein thrombosis (sudden unilateral swelling, calf pain), or significant worsening of symptoms

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While copper accumulation activates ferroptosis and cuproptosis in mammalian cells, knockdown of fdx-2 , a gene involved in cuproptosis, increased cold tolerance of wild-type C