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Who Should Be Careful Although the ColonBroom formulation is mostly safe, there are some situations where caution is needed: Pregnancy and Breastfeeding Berberine is generally not recommended during pregnancy or while breastfeeding

13 In this review, we summarise the evidence related to the effects of GLP-1 RAs on these outcomes ( Figure 1 ), which may shed light on the potential of these agents to be used in the clinical care of HF patients and investigated in large clinical trials to evaluate clinical outcomes

Clinicians should counsel women about risk for unintended pregnancy when starting GLP-1 therapy

Gandhi recommends either Semaglutide or Tirzepatide along with supporting therapies