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Both substances can independently cause hypoglycemia, and their combined use may amplify this effect

CF patients characteristically exhibit recurrent infections/inflammations of the respiratory tract, which is consistent with an increase in oxidative stress

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Despite its benefits, the clinical application of orlistat is often hindered by its gastrointestinal side effects and modest weight loss results, prompting the search for alternative and adjunct therapies, including natural products and novel PL inhibitory peptides that may offer better tolerability and effectiveness in managing obesity [7,8,9]