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Clinical studies have not established decreased libido as an official side effect, but the emerging case report literature and proposed neurochemical mechanisms suggest it occurs in a subset of women

In R161H mice, oral administration of broad-spectrum antibiotics (ampicillin, metronidazole, neomycin, and vancomycin, AMNV) starting from the pregnancy of the dam, and continuing the treatment after weaning in the offspring, significantly delayed the development of uveitis

And the combination can lead to dehydration and electrolyte imbalances if vomiting or diarrhea becomes persistent, which creates secondary risks for kidney function and overall metabolic stability

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