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Due to its unique research profile, Epithalon has attracted growing interest among researchers studying healthy ageing, biological resilience, and long-term cellular function

Semaglutide is an FDA-approved GLP-1 receptor agonist aimed at chronic weight management in individuals with obesity or overweight conditions accompanied by other health issues

Homologous recombination deficiency and ovarian cancer

Here, we propose SAGE-DM (Senescence-Associated Gluco-Endocrinopathy Diabetes Mellitus), a novel conceptual framework that extends the definition of so-called type 4 diabetes. SAGE-DM is characterised by insulin resistance and glucose dysregulation in lean or olders with sarcopenic obesity individuals, arising from endocrine senescence, chronic low-grade inflammation, and immunemetabolic crosstalk