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While the greater amount of cellular reduced GSH is found in the cytosol and mitochondria, the endoplasmic reticulum becomes a reservoir of small concentrations of the oxidized form of GSH (GSSG)

Jelveh et al

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The next sections will detail how polyphenolic compounds contribute to the reduction of ROS levels, mainly in the pathways that inhibit ROS generation and promote the elimination of existing ROS in the body (Fig