10.1016/S0954-6111(03)00026-X 80 GronebergD
Improved Bone Healing In addition to soft tissue, researchers have observed an increase in the rate of bone repair
This reversal was seen also on the background of the disturbed prostaglandins- and NO-systems, prostaglandins synthesis inhibition as well as NO-overstimulation (NOS-substrate L-arginine) or NO-blockade (N(G)-nitro-L-arginine methyl ester (L-NAME)) (Stupnisek et al., 2012
Nowadays, the regimens of cancer therapy, such as surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy, aim to induce the death of cancer cells to achieve a therapeutic effect, whereas the intrinsic and acquired resistance of cancer cells to cell death often results in far from satisfactory treatment outcomes (Loftus et al., 2022