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Tirzepatide 15 mg (the highest available dose) was the most effective in lowering A1c versus placebo (mean difference [MD], 2%, 95% CI -2.16 to -1.84), followed by tirzepatide 10 mg (MD -1.86%, 95% CI -2.02 to -1.84) and semaglutide 2 mg (MD, 95% CI -1.62%, -1.96 to -1.28)
"And that inflammatory state results in organ damage that leads to cardiometabolic disease, kidney disease, diabetes, certain forms of cancer, and potentially certain neurodegenerative changes," says Kessler
Most gastroenterologists advise against GLP-1 medications for patients with moderate to severe gastroparesis
Iyengar, S
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