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It can also cause loose stools in some individuals, and has undesirable filler ingredients like polyethylene glycols (PEG 400, PEG 8000), polysorbate 80, povidone, sodium lauryl sulfate, synthetic black iron oxides, and titanium dioxide

A marked difference in body weight gain is already apparent by day 8 (after the first week of METH operant intake): the short-access group gained over 20 grams, while the extended-access group increased by 10 grams, despite identical food intake

Diabetes 63 , 237247 (2014)